Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. There are currently no generic forms of either drug. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Its possible to get rid of or reduce the severity ofside effects. (Hemoglobin is a protein thats found in your red blood cells.). You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Depending on your doctors instructions and
Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Taking a higher dose than needed can often lead to adverse effects. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Injectafer contains the active drug ferric carboxymaltose. In Canada - Call your doctor for medical advice about side effects. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Very bad and sometimes deadly allergic side effects have rarely happened. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. People with IDA have low blood levels of hemoglobin. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. I can't take oral supplements because they cause horrible debilitating Constipation. If needed, theyll recommend treatment, including certain medications. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. This is not a complete list of possible side effects. Do not exceed 1,500 mg of iron per dosing course. If you notice any changes to your normal blood pressure, call your doctor right away. You may need extra iron because of blood loss during kidney dialysis. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. However, side effects at the 150 mg dose may indicate that you might not . Venofer Side Effects. (For more information on Venofer, see the Injectafer vs. Venofer section above). This information is not specific medical advice and does not replace information you receive from the healthcare provider. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. I was surprised too but the Dr said it definitely sounds like a reaction. reactions at the site of the injection. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Keep all drugs out of the reach of children and pets. Details. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This can be very helpful in . Theyll likely have you stop taking the pills while youre using Injectafer. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Nose or throat irritation. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Injectafer is approved to treat iron deficiency anemia (IDA). It is important to get each dose of this medication as scheduled. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Things to remember when you fill your prescription. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. With slow IV injection, the drug is given as a single, slow injection into your vein. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. Have blood work checked as you have been told by the doctor. Then your body uses that iron to make hemoglobin and RBCs. Understanding what thoseside effectsare can lead to a strategy to prevent them. Your healthcare provider will watch you closely for 30 minutes after each dose. This medication is given by injection into a vein as directed by your doctor. Review our medical disclaimer. After the infusion, you can drive yourself home and return to your usual activities. But so far I feel better than before the infusion. 4 0 obj Venofer injection contains iron sucrose, a form of the mineral iron. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Evenbirth controlcan lead to severeside effectslike bloodclots. weakness. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Not all possible drug interactions are listed here. If you have questions about using Injectafer in a child, talk with your doctor. Follow your doctor's directions carefully. With anemia, you have a low level of red blood cells (RBCs) in your body. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Pain, swelling, or redness at the injection site may occur. Any long-term side effects/dangers from iron infusions? He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Some drugs may have another patient information leaflet. We comply with the HONcode standard for trustworthy health information. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. In clinical trials,. endobj A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. Injectafer is a brand-name prescription drug. Hes an expert in genetic testing, genetic analysis, andprecision medicine. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. With IDA, you have low hemoglobin levels. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Brand-name medications usually cost more than generics. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. But you kidneys need iron in order to make EPO. Its possible that after getting two doses of Injectafer, your anemia may go away completely. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. The insurance company will review the prior authorization request and decide if the drug will be covered. If you notice other effects not listed above, contact your doctor or pharmacist. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Side effects are uncomfortable reactions to medications or drugs. Keep all regular medical and laboratory appointments. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Joint pain. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. It is given into a vein for a period of time. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Together, you and your doctor can develop a treatment plan thats best for you. Theseside effectsmay last as long as they are undercancer treatment. This includes your doctors, nurses, pharmacists, and dentists. <> This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Details. One of the most commonly used tests to monitor IDA is the hemoglobin test. Injectafer comes as a liquid solution inside vials. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. There isnt a known interaction between Injectafer and alcohol. There are 2 tests that your doctor will likely
Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. pain in the arms or legs. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. You should not receive Venofer if you have known allergies to iron sucrose. *Patients are calculated based on an estimated annual cumulative dose. Theseside effectscan range from being mild tosevere. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Generics tend to cost less than brand-name drugs. Injectafer isnt available in a generic form. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Call your doctor for medical advice about side effects. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. But for other people, doing so could lead to having too much iron in their body. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Most people do not know how long theirside effectswill last until they go through them. There have also been reports of serious allergic reactions to Venofer. But you dont necessarily need to eat these foods unless your doctor tells you to do so. This may be helped by giving the medication more slowly or at a lower dose. The information provided is not intended to replace your healthcare provider's medical advice. But some people have a delayed allergic reaction to certain drugs. Its responsible for carrying oxygen throughout your body. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. (Hemoglobin is a protein thats found inside your red blood cells.). If you think there has been an overdose, call your poison control center or get medical care right away. This means you would get two Injectafer doses of 720 mg each. Your doctor will go over your
Innovators Monograph administered at your doctors office or an infusion center. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. What is Venofer? wAd**CgI%"nn{Oa[q{r5 But keep in mind that in this study, delayed allergic reaction only occurred in one person. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. (And Injectafer is used to treat IDA.) Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. On day three I had a headache and felt heavy/exhausted, which lasted a few days. fever. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Both Injectafer and Venofer belong to a class of medications called iron replacement products. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. reese0809 1 yr. ago. Remember that it is best to get your vitamins and minerals from food whenever possible. Venofer is for use in adults and children at least 2 years old. This gives a total cumulative dose of 1,500 mg of Injectafer. MNT is the registered trade mark of Healthline Media. Why is the range so wide? This document does not contain all possible drug interactions. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Canada residents can call a provincial poison control center. Source: Wolters Kluwer Health. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Vomiting. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Find out what health conditions may be a health risk when taken with Venofer Vial Injectafer is available only as a brand-name medication. These side effects can range from being mild to severe. Check with your pharmacist. You may report side effects to FDA at 1-800-FDA-1088. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. endobj There are currently no generic forms of either drug. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. We cancelled my 5th because of the reaction. Low iron saturation, or iron deficiency, has various possible causes. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. % While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. And theyll recommend how soon after starting the drug you need to have this level checked. Below are examples of these side effects. These are not all the side effects that may occur; contact your healthcare provider if you have questions. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. <> Here we look at how Injectafer and Feraheme are alike and different. Do not start, stop, or change the dosage of any medicines without your doctor's approval. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Depending on your anemia symptoms, your weight changes may be different than those described here. Data on file, American Regent, Inc. 1. You will need to talk about the benefits and risks to you and the baby. Available for Android and iOS devices. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. upper respiratory infection. fever. This test measures the amount of hemoglobin in your blood. Keep all medications away from children and pets. Here we look at how Injectafer and Venofer are alike and different. I actually was constipated after my 3rd but didn't think anything of it. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Learn about uses, cost, how it works, and more. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Its not known if Injectafer is safe to use during pregnancy. Injectafer can cause mild or serious side effects. For example: Say you weigh 105 pounds (about 48 kilograms). This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. It depends. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Venofer is not for treating other forms of anemia not caused by iron deficiency. They can recommend appropriate treatment options. Effectiveness of Injectafer compared with iron thats taken by mouth. How long does iron infusion stay in your system? Following an LSD trip, users may experience a sort of 'comedown.'. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. This website is intended for use by US patients. I hope you found answers and are feeling better now. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Should I avoid certain foods while taking Venofer Vial? In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Theyll recommend how to manage your condition. . Injectafer isnt a medication that youll take regularly on a schedule. Read all information given to you. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. People from different ethnic backgrounds process medications differently. Medically reviewed by Sanjai Sinha, MD. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. endobj What are the side effects of Venofer? In the second group, some people switched from taking iron by mouth to taking Injectafer. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Here are answers to some frequently asked questions about Injectafer. Talk with the doctor. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). This medicine may cause serious types . Others last much longer (even a lifetime), which can be quite traumatizing to people. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Serious side effects from Injectafer arent common, but they can occur. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Check with your pharmacist if you have questions about the best way to throw out drugs. Properly discard this product when it is expired or no longer needed. Venofer is used to treat iron deficiency anemia in people with kidney disease. This site is intended for use only by US patients. Drug interactions may change how your medications work or increase your risk for serious side effects. This allows them to manage any side effects that you may have following your dose. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. And this can lead to anemia, including IDA. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). These are not all of the side effects that may occur. If you have symptoms of a low phosphorus level, call your doctor. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. They can recommend if this is safe for you to do.