If this worries you, talk to your doctor or pharmacist about other options. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Isosorbide mononitrate helps to prevent angina chest pain from developing. Herbal supplements can strongly affect the body. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. 8.0 out of 10 from a total of The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Botanical medicine A modern perspective. This survey is being conducted by the WebMD marketing sciences department. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Many common herbal supplements interact with common heart medicines. This drug may make you dizzy. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. Keep all medications away from children and pets. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty If you are a Mayo Clinic patient, this could Do not stop taking isosorbide without talking to your doctor. Things to remember when you fill your prescription. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. This is called a medicine interaction. Does Alcohol Raise Your Blood Pressure? You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. AskMayoExpert. Take care, thanks. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Journals of the American College of Cardiology. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Natural Medicines. Some don't work well with prescription medicines. View more. Do not share this medication with others. Upgrade to Patient Pro Medical Professional? Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Bethesda, MD 20894, Web Policies Would you like email updates of new search results? Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2017; doi:10.1016/j.jacc.2016.11.078. Conclusions: View interaction reports for isosorbide mononitrate and the medicines listed below. Careers. We study 23,548 Isosorbide mononitrate users. Is it safe to drive while on this medicine? Medicines containing Isosorbide Mononitrate. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Isosorbide dinitrate dose 30-120 mg daily in divided doses. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Drug information provided by: IBM Micromedex. The IR version can help treat and prevent angina. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Evening primrose. What special precautions should I follow? All rights reserved. Even if the medication is working, you may experience some unwanted side effects. Other medications may be prescribed by your doctor for these conditions. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. This content does not have an Arabic version. Selected from data included with permission and copyrighted by First Databank, Inc. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. 5.0 out of 10 from a total of Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Call your doctor if you have any unusual problems while you are taking this medication. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Ginkgo. This branded product is no longer on the market. This list covers only some interactions. Danshen. https://naturalmedicines.therapeuticresearch.com. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. you should know that you may experience headaches every day during your treatment with isosorbide. Use this medication regularly to get the most benefit from it. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Data were assessed for carryover and time effects. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. (2) One in 3 patients never experienced headache from the given dosages. Some conditions may become worse when the drug is suddenly stopped. Do not take two doses together to make up for a missed dose. Federal government websites often end in .gov or .mil. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. Select a condition to view a list of medication options. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. What are the side effects of Isosorbide Mononitrate ? You can start a phase IV clinical trial to monitor Isosorbide mononitrate safety and effectiveness. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). It can cause your blood pressure to become dangerously low. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. All rights reserved. May also be prescribed off label for Esophageal Spasm. Please enable it to take advantage of the complete set of features! Isosorbide mononitrate (Monoket) can cause some serious health issues. The .gov means its official. Please note that only the generic name of each medication is listed below. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Accessed Sept. 7, 2022. Never give it to other people even if their condition appears to be the same as yours. Never take more than the prescribed dose. Does Viagra add to the risks of melanoma? Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. The most common side-effect is headache. Keep this medication in the container it came in, tightly closed, and out of reach of children. We don't support your browser. https://naturalmedicines.therapeuticresearch.com. Natural Medicines. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. If it is within 2 hours of the next dose, skip the missed dose. Always consult your healthcare provider. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Methods: 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. WebMD does not provide medical advice, diagnosis or treatment. Keep all medicines out of the reach and sight of children. Bookshelf I would rather take the chance of a heart attack than have no quality of life. May also be prescribed off label for Esophageal Spasm. Am J Ther. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Isosorbide mononitrate: isosorbide mononitrate. This makes it easier for your heart to pump, relieving heart-related chest pain. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Talk to your pharmacist for more details. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. This information is aggregated and used to produce personalized reports that patients can reference. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. All rights reserved. Unable to load your collection due to an error, Unable to load your delegates due to an error. What happens if I stop taking isosorbide mononitrate (Monoket)? Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. https://naturalmedicines.therapeuticresearch.com. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. See also: nitroglycerin side effects in more detail. Generic alternatives may be available. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. If you have any problems with the way your liver works, or any problems with the way your kidneys work. This is not a complete list of possible side effects. A very serious allergic reaction to this drug is rare. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Elsevier; 2021. https://www.clinicalkey.com. Do not store in the bathroom. Isosorbide may cause other side effects. Change positions slowly until your body is used to the medication. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Natural Medicines. Which drugs or supplements interact with isosorbide mononitrate? Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. 8600 Rockville Pike Accessed Sept. 7, 2022. In: Current Medical Diagnosis & Treatment 2022. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease.